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Issue 4, 2012
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Development of novel ionic liquids based on ampicillin

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Abstract

Novel ionic liquids containing ampicillin as an active pharmaceutical ingredient anion were prepared with good yields by using a new, efficient synthetic procedure based on the neutralization of a moderately basic ammonia solution of ampicillin with different organic cation hydroxides. The relevant physical and thermal properties of these novel ionic liquids based on ampicillin were also evaluated.

Graphical abstract: Development of novel ionic liquids based on ampicillin

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Article information


Submitted
24 Oct 2011
Accepted
13 Feb 2012
First published
15 Feb 2012

Med. Chem. Commun., 2012,3, 494-497
Article type
Concise Article

Development of novel ionic liquids based on ampicillin

R. Ferraz, L. C. Branco, I. M. Marrucho, J. M. M. Araújo, L. P. N. Rebelo, M. N. da Ponte, C. Prudêncio, J. P. Noronha and Ž. Petrovski, Med. Chem. Commun., 2012, 3, 494
DOI: 10.1039/C2MD00269H

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