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Issue 1, 2012
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Inhibitors of Stat5 protein signalling

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Abstract

Evidence shows that signal transducer and activator of transcription 5 (Stat5) protein, a member of the STAT family of signalling proteins, plays a pivotal role in the progression of many human cancers including acute myeloid leukemias and prostate cancer. This mini-review outlines progress made towards identifying agents capable of silencing aberrant Stat5 signalling.

Graphical abstract: Inhibitors of Stat5 protein signalling

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Publication details

The article was received on 07 Jul 2011, accepted on 25 Aug 2011 and first published on 03 Oct 2011


Article type: Review Article
DOI: 10.1039/C1MD00175B
Citation: Med. Chem. Commun., 2012,3, 22-27

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    Inhibitors of Stat5 protein signalling

    A. A. Cumaraswamy, A. Todic, D. Resetca, M. D. Minden and P. T. Gunning, Med. Chem. Commun., 2012, 3, 22
    DOI: 10.1039/C1MD00175B

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