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As the usage of fluorescence microscopy as a tool to study biological systems continues to grow, so does the need for additional tools that permit the selective detection of proteins of interest. Existing selective and well-characterized kinase inhibitors may be exploited to develop novel small molecule probes useful in imaging kinases by fluorescence microscopy.

Graphical abstract: Leveraging kinase inhibitors to develop small molecule tools for imaging kinases by fluorescence microscopy

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