Issue 32, 2012
From the journal:

Journal of Materials Chemistry

Microfabrication of mesoporous silica encapsulated enzymes using deep X-ray lithography†

Cara M. Doherty,*a   Yuan Gao,a   Benedetta Marmiroli,b   Heinz Amenitsch,b   Fabio Lisi,ac   Luca Malfatti,d   Kenji Okada,e   Masahide Takahashi,e   Anita J. Hill,af   Plinio Innocenzid  and  Paolo Falcaro*a  

* Corresponding authors

a CSIRO Materials Science and Engineering, Private Bag 33, Clayton, South MDC, Victoria 3169, Australia
E-mail: cara.doherty@csiro.au, paolo.falcaro@csiro.au

b Institute of Biophysics and Nanosystems Research, Austrian Academy of Sciences, Schmiedlstraße 6, Graz, Austria

c School of Chemistry and Bio21 Institute, University of Melbourne, Parkville, Victoria, Australia

d Laboratorio di Scienza dei Materiali e Nanotecnologie (LMNT), INSTM and CNBS, Universit a di Sassari, Palazzo Pou Salid, Piazza Duomo 6, 07041 Alghero, SS, Italy

e Graduate School of Engineering, Osaka Prefecture University, Sakai, Osaka 599-8531, Japan

f CSIRO Process Science and Engineering, Private Bag 33, Clayton, South MDC, Victoria 3169, Australia

Abstract

A bottom-up enzyme encapsulation technique on mesoporous silica together with top-down deep X-ray lithography provides a novel fabrication method for producing bioactive mesoporous patterned substrates for potential use as a biosensing platform. This precise, spatially controllable functionalisation technique is promising for micro-fluidic or lab-on-a-chip type devices.

Graphical abstract: Microfabrication of mesoporous silica encapsulated enzymes using deep X-ray lithography

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Article information

DOI
https://doi.org/10.1039/C2JM32863A
Article type
Communication
Submitted
07 May 2012
Accepted
02 Jul 2012
First published
03 Jul 2012

J. Mater. Chem., 2012,22, 16191-16195

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Microfabrication of mesoporous silica encapsulated enzymes using deep X-ray lithography

C. M. Doherty, Y. Gao, B. Marmiroli, H. Amenitsch, F. Lisi, L. Malfatti, K. Okada, M. Takahashi, A. J. Hill, P. Innocenzi and P. Falcaro, J. Mater. Chem., 2012, 22, 16191 DOI: 10.1039/C2JM32863A

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