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Issue 13, 2012
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Bifunctional Janus beads made by “sandwich” microcontact printing using click chemistry

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This article describes the preparation of spherical Janus particles by microcontact printing. A set of three different polymer beads (diameter ca. 170 μm), each bearing different functional groups at their surface, are used to covalently attach distinct functional molecules exclusively on opposing poles of the beads. The covalent modification of the beads involves three different types of click chemistry: epoxide ring opening (ERO), copper catalysed azide–alkyne cycloaddition (CuAAC) and thiol–yne addition (TYA). These reactions are compared with regard to their advantages and disadvantages in the context of “sandwich” microcontact chemistry. The success of surface modification of the beads is verified by fluorescence microscopy and 3D-time of flight secondary ion mass spectrometry measurements and is further supported by reference experiments on planar surfaces bearing the same surface functionality and analysed by X-ray photoelectron spectroscopy, secondary ion mass spectrometry, atomic force microscopy and fluorescence microscopy. Furthermore we demonstrate that sandwich microcontact printing can also be performed on smaller polymer beads with a diameter of ca. 5 μm. The broad scope of surface chemistry in combination with the simple experimental setup makes this method attractive to a wide range of material science applications, since it combines orthogonality of surface functionalization with high pattern fidelity.

Graphical abstract: Bifunctional Janus beads made by “sandwich” microcontact printing using click chemistry

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Publication details

The article was received on 23 Dec 2011, accepted on 26 Jan 2012 and first published on 17 Feb 2012

Article type: Paper
DOI: 10.1039/C2JM16807C
Citation: J. Mater. Chem., 2012,22, 6190-6199

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    Bifunctional Janus beads made by “sandwich” microcontact printing using click chemistry

    T. Kaufmann, M. T. Gokmen, S. Rinnen, H. F. Arlinghaus, F. Du Prez and B. J. Ravoo, J. Mater. Chem., 2012, 22, 6190
    DOI: 10.1039/C2JM16807C

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