Issue 21, 2012

A novel conjugate of a cell-penetrating peptide and a ferrocenyl amino acid: a potential electrochemical sensor for living cells?

Abstract

The conjugation of a ferrocenyl amino acid to the cell-penetrating peptide hCT(9–32) does not impair its ability to efficiently translocate into cells. Furthermore, the bioconjugate does not induce any cytotoxicity, thus presenting a potential electrochemical sensor suitable for the detection of living cells.

Graphical abstract: A novel conjugate of a cell-penetrating peptide and a ferrocenyl amino acid: a potential electrochemical sensor for living cells?

Article information

Article type
Communication
Submitted
18 Nov 2011
Accepted
27 Feb 2012
First published
14 Mar 2012

Dalton Trans., 2012,41, 6396-6398

A novel conjugate of a cell-penetrating peptide and a ferrocenyl amino acid: a potential electrochemical sensor for living cells?

J. Hoyer, A. Hunold, H. Schmalz and I. Neundorf, Dalton Trans., 2012, 41, 6396 DOI: 10.1039/C2DT12211A

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