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Issue 8, 2012
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Different strategies to enhance the activity of lipase catalysts

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Abstract

The design of new strategies for improving the catalytic activity of lipases in their application on non-natural substrates is in great demand due to their biotechnological applications. This perspective illustrates the power of technologies, such as the immobilization of enzymes on nanomaterials and the site-specific chemical modification of enzyme surfaces, to prepare highly active semisynthetic lipases. These techniques have produced optimal biocatalysts for different important bioprocesses such as biodiesel production, regioselective deprotection of carbohydrates and kinetic resolution of different drug precursors.

Graphical abstract: Different strategies to enhance the activity of lipase catalysts

  • This article is part of the themed collection: Biocatalysis
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Publication details

The article was received on 15 Dec 2011, accepted on 07 May 2012 and first published on 22 Jun 2012


Article type: Perspective
DOI: 10.1039/C2CY20125A
Catal. Sci. Technol., 2012,2, 1531-1543

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    Different strategies to enhance the activity of lipase catalysts

    M. Marciello, M. Filice and J. M. Palomo, Catal. Sci. Technol., 2012, 2, 1531
    DOI: 10.1039/C2CY20125A

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