Issue 2, 2012

Resonance scattering particles as biological nanosensors in vitro and in vivo

Abstract

Recently dark-field microscopy and Rayleigh scattering spectroscopy have emerged as complementary technologies for ultrasensitive biological detection and imaging with high spatial and temporal resolution. Plasmonic resonant nanoparticles are key nano-scale probes for these technologies that have enabled single-molecule sensitivity and imaging. In this tutorial review, we focus on the use of plasmonic probes as single-particle biological nanosensors in vitro and in vivo. The progress in this field over the last decade will be highlighted.

Graphical abstract: Resonance scattering particles as biological nanosensors in vitro and in vivo

Article information

Article type
Tutorial Review
Submitted
27 May 2011
First published
19 Aug 2011

Chem. Soc. Rev., 2012,41, 632-642

Resonance scattering particles as biological nanosensors in vitro and in vivo

Y. Li, C. Jing, L. Zhang and Y. Long, Chem. Soc. Rev., 2012, 41, 632 DOI: 10.1039/C1CS15143F

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