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Issue 19, 2013
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Cancer cell detection based on the interaction between an anticancer drug and cell membrane components

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Abstract

Simple and general cancer cell detection methods are required in point-of-care diagnostics. Herein, the interaction between an anticancer drug, daunomycin, and cancer cell membrane components has been studied using an aptamer probe immobilized on a conducting polymergold nanoparticle composite film through electrochemical and fluorescence methods and applied to the quantitative detection of cancer cells. The developed method differentiates between cancerous and noncancerous cells effectively.

Graphical abstract: Cancer cell detection based on the interaction between an anticancer drug and cell membrane components

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Publication details

The article was received on 15 Nov 2012, accepted on 20 Dec 2012 and first published on 21 Dec 2012


Article type: Communication
DOI: 10.1039/C2CC38235K
Citation: Chem. Commun., 2013,49, 1900-1902
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    Cancer cell detection based on the interaction between an anticancer drug and cell membrane components

    P. Chandra, H. Noh and Y. Shim, Chem. Commun., 2013, 49, 1900
    DOI: 10.1039/C2CC38235K

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