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Issue 72, 2012
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I2 promoted domino oxidative cyclization for one-pot synthesis of 2-acylbenzothiazoles via metal-free sp3 C–H functionalization

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Abstract

An I2 promoted domino protocol was developed to construct 2-acylbenzothiazoles from simple and readily available aromatic ketones/unsaturated methyl ketones and o-aminobenzenethiols. The reaction proceeded smoothly under metal-free and peroxide-free conditions.

Graphical abstract: I2 promoted domino oxidative cyclization for one-pot synthesis of 2-acylbenzothiazoles via metal-free sp3 C–H functionalization

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Article information


Submitted
26 Jun 2012
Accepted
19 Jul 2012
First published
24 Jul 2012

Chem. Commun., 2012,48, 9086-9088
Article type
Communication

I2 promoted domino oxidative cyclization for one-pot synthesis of 2-acylbenzothiazoles via metal-free sp3 C–H functionalization

Y. Zhu, M. Lian, F. Jia, M. Liu, J. Yuan, Q. Gao and A. Wu, Chem. Commun., 2012, 48, 9086
DOI: 10.1039/C2CC34561G

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