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Issue 71, 2012
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Palladium-catalyzed direct arylation of benzoxazoles with unactivated simple arenes

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Abstract

Using CuBr2 as an additive, the Pd-catalyzed intermolecular C–H–C–H cross-coupling between benzoxazoles and unactivated simple arenes has been developed. This protocol provides a straightforward approach for the biological activity of 2-arylbenzoxazole derivatives.

Graphical abstract: Palladium-catalyzed direct arylation of benzoxazoles with unactivated simple arenes

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Supplementary files

Article information


Submitted
13 Jun 2012
Accepted
14 Jul 2012
First published
16 Jul 2012

Chem. Commun., 2012,48, 8964-8966
Article type
Communication

Palladium-catalyzed direct arylation of benzoxazoles with unactivated simple arenes

G. Wu, J. Zhou, M. Zhang, P. Hu and W. Su, Chem. Commun., 2012, 48, 8964
DOI: 10.1039/C2CC34238C

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