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Issue 67, 2012
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Microbubble–sonosensitiser conjugates as therapeutics in sonodynamic therapy

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Abstract

A Rose Bengal sonosensitiser has been covalently attached to a lipid microbubble and the resulting conjugate shown to produce higher levels of singlet oxygen, enhanced cytotoxicity in a cancer cell line and a greater reduction in tumour growth than the sonosensitiser alone.

Graphical abstract: Microbubble–sonosensitiser conjugates as therapeutics in sonodynamic therapy

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Article information


Submitted
31 May 2012
Accepted
20 Jun 2012
First published
21 Jun 2012

Chem. Commun., 2012,48, 8332-8334
Article type
Communication

Microbubble–sonosensitiser conjugates as therapeutics in sonodynamic therapy

N. Nomikou, C. Fowley, N. M. Byrne, B. McCaughan, A. P. McHale and J. F. Callan, Chem. Commun., 2012, 48, 8332
DOI: 10.1039/C2CC33913G

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