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Issue 65, 2012
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Fully automated sequential solid phase approach towards viral RNA-nucleopeptides

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Abstract

The synthesis of two ribonucleoprotein fragments of unprecedented complexity is reported. These hybrid biomolecules are prepared combining the use of an automated solid phase peptide and oligonucleotide synthesizer on a single solid support.

Graphical abstract: Fully automated sequential solid phase approach towards viral RNA-nucleopeptides

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Publication details

The article was received on 14 May 2012, accepted on 27 Jun 2012 and first published on 28 Jun 2012


Article type: Communication
DOI: 10.1039/C2CC33477A
Chem. Commun., 2012,48, 8093-8095

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    Fully automated sequential solid phase approach towards viral RNA-nucleopeptides

    G. J. van der Heden van Noort, P. V. Delft, N. J. Meeuwenoord, H. S. Overkleeft, G. A. van der Marel and D. V. Filippov, Chem. Commun., 2012, 48, 8093
    DOI: 10.1039/C2CC33477A

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