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Issue 67, 2012
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Chemical speciation of nanoparticles surrounding metal-on-metal hips

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Abstract

Spectromicroscopy of tissue surrounding failed CoCr metal-on-metal hip replacements detected corroded nanoscale debris in periprosthetic tissue in two chemical states, with concomitant mitochondrial damage. The majority of debris contained Cr3+, with trace amounts of oxidised cobalt. A minority phase containing a core of metallic chromium and cobalt was also observed.

Graphical abstract: Chemical speciation of nanoparticles surrounding metal-on-metal hips

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Article information


Submitted
26 Apr 2012
Accepted
12 Jun 2012
First published
13 Jun 2012

Chem. Commun., 2012,48, 8335-8337
Article type
Communication

Chemical speciation of nanoparticles surrounding metal-on-metal hips

A. E. Goode, J. M. Perkins, A. Sandison, C. Karunakaran, H. Cheng, D. Wall, J. A. Skinner, A. J. Hart, A. E. Porter, D. W. McComb and M. P. Ryan, Chem. Commun., 2012, 48, 8335
DOI: 10.1039/C2CC33016D

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