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Issue 51, 2012
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Femtomolar detection of a cancer biomarkerprotein in serum with ultralow background current by anodic stripping voltammetry

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Abstract

An electrochemical immunosensor for the detection of a cancer biomarker protein in serum at femtomolar concentrations with ultralow background response has been developed, which consists of (i) a hydrophilic polyacrylic acid brush-modified indium tin oxide substrate as an antifouling substrate and (ii) a graphenequantum dots–antibody ‘bionanoconjugate’ as a signal amplification label in voltammetric detection of targets in a glassy carbon electrode.

Graphical abstract: Femtomolar detection of a cancer biomarker protein in serum with ultralow background current by anodic stripping voltammetry

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Article information


Submitted
02 Mar 2012
Accepted
01 May 2012
First published
01 May 2012

Chem. Commun., 2012,48, 6411-6413
Article type
Communication

Femtomolar detection of a cancer biomarker protein in serum with ultralow background current by anodic stripping voltammetry

M. J. A. Shiddiky, P. H. Kithva, S. Rauf and M. Trau, Chem. Commun., 2012, 48, 6411
DOI: 10.1039/C2CC32810K

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