Issue 47, 2012
From the journal:

Chemical Communications

A highly sensitive, multiplex immunoassay using gold nanoparticle-enhanced signal amplification†

Ki-Cheol Han,a   Eun Gyeong Yang*ab  and  Dae-Ro Ahn*ac  

* Corresponding authors

a Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, Hwarangno 14-gil 5, Seongbuk-gu, Seoul 136-791, Republic of Korea
E-mail: drahn@kist.re.kr
Fax: +82 2 958 5909
Tel: +82 2 958 6645

b Functional Proteomics Center, Korea Institute of Science and Technology, Hwarangno 14-gil 5, Seongbuk-gu, Seoul 136-791, Republic of Korea
E-mail: eunyang@kist.re.kr
Fax: +82 2 958 5909
Tel: +82 2 958 5178

c KIST Campus, University of Science and Technology (UST), Hwarangno 14-gil 5, Seongbuk-gu, Seoul 136-791, Republic of Korea

Abstract

We describe a highly sensitive, multiplex immunoassay utilizing gold nanoparticles for conjugation of detection antibodies with signal generators. The method has been compared with conventional methods and evaluated for simultaneous detection of two different biomarkers in human serum.

Graphical abstract: A highly sensitive, multiplex immunoassay using gold nanoparticle-enhanced signal amplification

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Article information

DOI
https://doi.org/10.1039/C2CC31659E
Article type
Communication
Submitted
06 Mar 2012
Accepted
18 Apr 2012
First published
18 Apr 2012

Chem. Commun., 2012,48, 5895-5897

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A highly sensitive, multiplex immunoassay using gold nanoparticle-enhanced signal amplification

K. Han, E. G. Yang and D. Ahn, Chem. Commun., 2012, 48, 5895 DOI: 10.1039/C2CC31659E

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