Issue 37, 2012
From the journal:

Chemical Communications

A cascade reaction of pyrrole-2-carbaldehyde substituted Morita–Baylis–Hillman adducts in the presence of tetrabutylammonium hydroxide or acetate to construct aza-heterocycles†

Long Huanga  and  Min Shi*ab  

* Corresponding authors

a Key Laboratory for Advanced Materials and Institute of Fine Chemicals, East China University of Science and Technology, and 130 MeiLong Road, Shanghai 200237, P. R. China

b State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, P. R. China
E-mail: mshi@mail.sioc.ac.cn

Abstract

The phase-transfer catalyst promoted intramolecular transformation of pyrrole-2-carbaldehyde substituted Morita–Baylis–Hillman adducts has been disclosed, providing an efficient way to construct pyrrolo[1,2-a]azepin-7(6H)-one skeletons in moderate to good yields (up to 92%) under mild conditions.

Graphical abstract: A cascade reaction of pyrrole-2-carbaldehyde substituted Morita–Baylis–Hillman adducts in the presence of tetrabutylammonium hydroxide or acetate to construct aza-heterocycles

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C2CC31358H
Article type
Communication
Submitted
23 Feb 2012
Accepted
14 Mar 2012
First published
14 Mar 2012

Chem. Commun., 2012,48, 4501-4503

Permissions

Request permissions

A cascade reaction of pyrrole-2-carbaldehyde substituted Morita–Baylis–Hillman adducts in the presence of tetrabutylammonium hydroxide or acetate to construct aza-heterocycles

L. Huang and M. Shi, Chem. Commun., 2012, 48, 4501 DOI: 10.1039/C2CC31358H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements