Issue 36, 2012
From the journal:

Chemical Communications

Total synthesis and absolute configuration of nocardioazine B†

Mingzhong Wang,a   Xiangyang Feng,ab   Liangzhen Cai,b   Zhengshuang Xu*ac  and  Tao Ye*ac  

* Corresponding authors

a Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, University Town of Shenzhen, Xili, Nanshan District, Shenzhen, China
E-mail: bctaoye@inet.polyu.edu.hk, xuzs@pkusz.edu.cn

b School of Chemistry and Molecular Engineering, East China University of Science and Technology, Meilong Road 130, Shanghai, China

c Department of Applied Biology & Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China
E-mail: bctaoye@inet.polyu.edu.hk
Tel: +852 34008722

Abstract

The first total synthesis of the indole alkaloid nocardioazine B was accomplished in 10 steps with an overall yield of 11.8%, establishing the absolute stereochemistry of the natural product.

Graphical abstract: Total synthesis and absolute configuration of nocardioazine B

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Article information

DOI
https://doi.org/10.1039/C2CC31025B
Article type
Communication
Submitted
12 Feb 2012
Accepted
14 Mar 2012
First published
14 Mar 2012

Chem. Commun., 2012,48, 4344-4346

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Total synthesis and absolute configuration of nocardioazine B

M. Wang, X. Feng, L. Cai, Z. Xu and T. Ye, Chem. Commun., 2012, 48, 4344 DOI: 10.1039/C2CC31025B

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