Jump to main content
Jump to site search

Issue 37, 2012
Previous Article Next Article

Phosphine-boronates: efficient bifunctional organocatalysts for Michael addition

Author affiliations

Abstract

Phosphine-boronates R2P(o-C6H4)B(OR′)2 have been evaluated as bifunctional organocatalysts for the Michael addition of malonate pronucleophiles to methylvinylketone. The presence of the Lewis acidic boron center adjacent to phosphorus significantly improves catalytic performance. Isolation and complete characterization of a key intermediate, namely a β-phosphonium enolate, substantiate the role of the Lewis acidic moiety in the catalytic process.

Graphical abstract: Phosphine-boronates: efficient bifunctional organocatalysts for Michael addition

Back to tab navigation

Supplementary files

Article information


Submitted
17 Jan 2012
Accepted
14 Mar 2012
First published
15 Mar 2012

Chem. Commun., 2012,48, 4495-4497
Article type
Communication

Phosphine-boronates: efficient bifunctional organocatalysts for Michael addition

O. Baslé, S. Porcel, S. Ladeira, G. Bouhadir and D. Bourissou, Chem. Commun., 2012, 48, 4495 DOI: 10.1039/C2CC30399J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.


Social activity

Search articles by author

Spotlight

Advertisements