Et3N-promoted tandem ring-opening reaction of N-tosylaziridines with terminal alkynoates: a straightforward synthesis of functionalized enamines

Abstract

A tandem ring-opening reaction of N-tosylaziridines with terminal alkynoates promoted by Et₃N has been described. A variety of N-tosylaziridines reacted with terminal alkynoates to give functionalized enamines in moderate to good yields under simple reaction conditions.