Issue 22, 2012

Occurrence of spontaneous resolution of ketoprofen with a racemic crystal structure by simple crystallization under nonequilibrium preferential enrichment conditions

Abstract

Nearly racemic ketoprofen, which satisfies the requirements for the occurrence of preferential enrichment, was spontaneously resolved into the two enantiomers by simple crystallization under nonequilibrium conditions using high concentrations.

Graphical abstract: Occurrence of spontaneous resolution of ketoprofen with a racemic crystal structure by simple crystallization under nonequilibrium preferential enrichment conditions

  • This article is part of the themed collection: Chirality

Supplementary files

Additions and corrections

Article information

Article type
Communication
Submitted
29 Dec 2011
Accepted
26 Jan 2012
First published
27 Jan 2012

Chem. Commun., 2012,48, 2791-2793

Occurrence of spontaneous resolution of ketoprofen with a racemic crystal structure by simple crystallization under nonequilibrium preferential enrichment conditions

R. G. Gonnade, S. Iwama, R. Sugiwake, K. Manoj, H. Takahashi, H. Tsue and R. Tamura, Chem. Commun., 2012, 48, 2791 DOI: 10.1039/C2CC18132K

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