Issue 25, 2012

Aza-oxindole synthesis by oxidative coupling of Csp2–H and Csp3–H centers

Abstract

A Cu(II) mediated oxidative Csp2–H and Csp3–H coupling protocol gives access to aza-oxindoles in good to excellent yield in the presence of NaOtBu as base and toluene as solvent.

Graphical abstract: Aza-oxindole synthesis by oxidative coupling of Csp2–H and Csp3–H centers

Supplementary files

Article information

Article type
Communication
Submitted
16 Dec 2011
Accepted
27 Jan 2012
First published
30 Jan 2012

Chem. Commun., 2012,48, 3064-3066

Aza-oxindole synthesis by oxidative coupling of Csp2–H and Csp3–H centers

C. Dey and E. P. Kündig, Chem. Commun., 2012, 48, 3064 DOI: 10.1039/C2CC17871K

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