Issue 8, 2012

Chemiluminescence biosensors for DNA detection using graphene oxide and a horseradish peroxidase-mimicking DNAzyme

Abstract

In this communication, we demonstrate that graphene oxide (GO) greatly inhibits the peroxidatic activity of a horseradish peroxidase-mimicking DNAzyme. Combining this observation with the unique DNA/GO interactions, an ultrasensitive GO-based chemiluminescence DNA biosensing platform is developed.

Graphical abstract: Chemiluminescence biosensors for DNA detection using graphene oxide and a horseradish peroxidase-mimicking DNAzyme

Supplementary files

Article information

Article type
Communication
Submitted
06 Nov 2011
Accepted
21 Nov 2011
First published
24 Nov 2011

Chem. Commun., 2012,48, 1126-1128

Chemiluminescence biosensors for DNA detection using graphene oxide and a horseradish peroxidase-mimicking DNAzyme

M. Luo, X. Chen, G. Zhou, X. Xiang, L. Chen, X. Ji and Z. He, Chem. Commun., 2012, 48, 1126 DOI: 10.1039/C2CC16868E

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