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Issue 10, 2012
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Clickosomes—using triazole-linked phospholipid connectors to fuse vesicles

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Abstract

Two complementary artificial diether phospholipids were synthesized that can undergo a Cu(I)-catalyzed Huisgen–Sharpless click reaction. The resulting lipid can bridge the membranes of large unilamellar vesicles and cause their aggregation and ultimately their fusion.

Graphical abstract: Clickosomes—using triazole-linked phospholipid connectors to fuse vesicles

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Publication details

The article was received on 03 Nov 2011, accepted on 23 Nov 2011 and first published on 24 Nov 2011


Article type: Communication
DOI: 10.1039/C2CC16827H
Citation: Chem. Commun., 2012,48, 1604-1606

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    Clickosomes—using triazole-linked phospholipid connectors to fuse vesicles

    F. Loosli, D. A. Doval, D. Grassi, P. Zaffalon, F. Favarger and A. Zumbuehl, Chem. Commun., 2012, 48, 1604
    DOI: 10.1039/C2CC16827H

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