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Issue 10, 2012
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Clickosomes—using triazole-linked phospholipid connectors to fuse vesicles

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Abstract

Two complementary artificial diether phospholipids were synthesized that can undergo a Cu(I)-catalyzed Huisgen–Sharpless click reaction. The resulting lipid can bridge the membranes of large unilamellar vesicles and cause their aggregation and ultimately their fusion.

Graphical abstract: Clickosomes—using triazole-linked phospholipid connectors to fuse vesicles

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Article information


Submitted
03 Nov 2011
Accepted
23 Nov 2011
First published
24 Nov 2011

Chem. Commun., 2012,48, 1604-1606
Article type
Communication

Clickosomes—using triazole-linked phospholipid connectors to fuse vesicles

F. Loosli, D. A. Doval, D. Grassi, P. Zaffalon, F. Favarger and A. Zumbuehl, Chem. Commun., 2012, 48, 1604
DOI: 10.1039/C2CC16827H

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