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Issue 73, 2012
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Increasing materials' response to two-photon NIR light via self-immolative dendritic scaffolds

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Abstract

Photoactivation using two photons of NIR allows non-invasive biological manipulation. We applied the principle of dendritic amplification to improve the materials' sensitivity to NIR light. Light induced uncaging or release of L-glutamic acid was 2.8 fold higher when incorporating 4-bromo-7-hydroxycoumarin (Bhc) with self-immolative dendrimers compared with Bhc directly conjugated to L-glutamic acid.

Graphical abstract: Increasing materials' response to two-photon NIR light via self-immolative dendritic scaffolds

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Article information


Submitted
05 Jan 2012
Accepted
16 Mar 2012
First published
19 Mar 2012

Chem. Commun., 2012,48, 9138-9140
Article type
Communication

Increasing materials' response to two-photon NIR light via self-immolative dendritic scaffolds

N. Fomina, C. L. McFearin and A. Almutairi, Chem. Commun., 2012, 48, 9138
DOI: 10.1039/C2CC00072E

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