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Issue 6, 2012
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Robust antimicrobial compounds and polymers derived from natural resin acids

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Abstract

We report novel robust resin acid-derived antimicrobial agents that exhibit excellent antimicrobial activities against a broad spectrum of bacteria (6 Gram-positive and 7 Gram-negative) with selective lysis of microbial membranes over mammalian membranes. Our results indicate that hydrophobicity and unique structures of resin acids can be determining factors in dictating the antimicrobial activity.

Graphical abstract: Robust antimicrobial compounds and polymers derived from natural resin acids

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Publication details

The article was received on 16 Oct 2011, accepted on 17 Nov 2011 and first published on 17 Nov 2011


Article type: Communication
DOI: 10.1039/C1CC16432E
Citation: Chem. Commun., 2012,48, 916-918
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    Robust antimicrobial compounds and polymers derived from natural resin acids

    J. Wang, Y. P. Chen, K. Yao, P. A. Wilbon, W. Zhang, L. Ren, J. Zhou, M. Nagarkatti, C. Wang, F. Chu, X. He, A. W. Decho and C. Tang, Chem. Commun., 2012, 48, 916
    DOI: 10.1039/C1CC16432E

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