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Issue 6, 2012
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Robust antimicrobial compounds and polymers derived from natural resin acids

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Abstract

We report novel robust resin acid-derived antimicrobial agents that exhibit excellent antimicrobial activities against a broad spectrum of bacteria (6 Gram-positive and 7 Gram-negative) with selective lysis of microbial membranes over mammalian membranes. Our results indicate that hydrophobicity and unique structures of resin acids can be determining factors in dictating the antimicrobial activity.

Graphical abstract: Robust antimicrobial compounds and polymers derived from natural resin acids

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Supplementary files

Article information


Submitted
16 Oct 2011
Accepted
17 Nov 2011
First published
17 Nov 2011

Chem. Commun., 2012,48, 916-918
Article type
Communication

Robust antimicrobial compounds and polymers derived from natural resin acids

J. Wang, Y. P. Chen, K. Yao, P. A. Wilbon, W. Zhang, L. Ren, J. Zhou, M. Nagarkatti, C. Wang, F. Chu, X. He, A. W. Decho and C. Tang, Chem. Commun., 2012, 48, 916
DOI: 10.1039/C1CC16432E

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