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Issue 12, 2012
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Enzyme responsive luminescent ruthenium(ii) cephalosporin probe for intracellular imaging and photoinactivation of antibiotics resistant bacteria

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Abstract

The Főrster resonance energy transfer (FRET) based luminescent ruthenium(II) cephalosporin probe has been designed and synthesized, which can be selectively activated by endogenous β-lactamases and thus provided a localized and specific intracellular luminescence imaging and photoinactivation of drug resistant bacterial pathogens.

Graphical abstract: Enzyme responsive luminescent ruthenium(ii) cephalosporin probe for intracellular imaging and photoinactivation of antibiotics resistant bacteria

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Supplementary files

Article information


Submitted
04 Oct 2011
Accepted
25 Oct 2011
First published
07 Nov 2011

Chem. Commun., 2012,48, 1739-1741
Article type
Communication

Enzyme responsive luminescent ruthenium(II) cephalosporin probe for intracellular imaging and photoinactivation of antibiotics resistant bacteria

Q. Shao and B. Xing, Chem. Commun., 2012, 48, 1739
DOI: 10.1039/C1CC16165B

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