Issue 6, 2012
From the journal:

Chemical Communications

Bifunctional peptides that precisely biomineralize Au clusters and specifically stain cell nuclei†

Yaling Wang,a   Yanyan Cui,a   Yuliang Zhao,*a   Ru Liu,a   Zhipeng Sun,a   Wei Lia  and  Xueyun Gao*a  

* Corresponding authors

a Institute of High Energy Physics, Chinese Academy of Sciences, Yuquan Road 19B, Shi Jing Shan District, Beijing 10049, China
E-mail: gaoxy@ihep.ac.cn, zhaoyuliang@ihep.ac.cn
Fax: 86-10-88236456
Tel: 86-10-88236709

Abstract

A bifunctional peptide containing a domain that targets cell nuclei and a domain with the ability to biomineralize and capture Au clusters is presented. The peptide–Au clusters exhibit red emission (λem = 677 nm) and specifically stain the nuclei of three cell lines.

Graphical abstract: Bifunctional peptides that precisely biomineralize Au clusters and specifically stain cell nuclei

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Article information

DOI
https://doi.org/10.1039/C1CC15926G
Article type
Communication
Submitted
23 Sep 2011
Accepted
08 Nov 2011
First published
01 Dec 2011

Chem. Commun., 2012,48, 871-873

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Bifunctional peptides that precisely biomineralize Au clusters and specifically stain cell nuclei

Y. Wang, Y. Cui, Y. Zhao, R. Liu, Z. Sun, W. Li and X. Gao, Chem. Commun., 2012, 48, 871 DOI: 10.1039/C1CC15926G

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