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Issue 10, 2012
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A modular system for regeneration of NADcofactors using graphite particles modified with hydrogenase and diaphorase moieties

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Abstract

Pyrolytic graphite particles modified with hydrogenase and an NAD+/NADH cycling enzyme provide a modular heterogeneous catalyst system for regeneration of oxidised or reduced nicotinamide cofactors using H2 and H+ as electron source or sink. Particles can be tuned for cofactor supply under different conditions by appropriate choice of hydrogenase.

Graphical abstract: A modular system for regeneration of NAD cofactors using graphite particles modified with hydrogenase and diaphorase moieties

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Supplementary files

Article information


Submitted
04 Aug 2011
Accepted
21 Sep 2011
First published
10 Oct 2011

Chem. Commun., 2012,48, 1589-1591
Article type
Communication

A modular system for regeneration of NAD cofactors using graphite particles modified with hydrogenase and diaphorase moieties

H. A. Reeve, L. Lauterbach, P. A. Ash, O. Lenz and K. A. Vincent, Chem. Commun., 2012, 48, 1589 DOI: 10.1039/C1CC14826E

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