Jump to main content
Jump to site search

Issue 10, 2012
Previous Article Next Article

Iron-catalysed, hydride-mediated reductive cross-coupling of vinyl halides and Grignard reagents

Author affiliations

Abstract

An iron-catalysed, hydride-mediated reductive cross-coupling reaction has been developed for the preparation of alkanes. Using a bench-stable iron(II) pre-catalyst, reductive cross-coupling of vinyl iodides, bromides and chlorides with aryl- and alkyl Grignard reagents successfully gave the products of formal sp3–sp3 cross-coupling reactions.

Graphical abstract: Iron-catalysed, hydride-mediated reductive cross-coupling of vinyl halides and Grignard reagents

Back to tab navigation

Supplementary files

Article information


Submitted
28 Jul 2011
Accepted
14 Oct 2011
First published
31 Oct 2011

Chem. Commun., 2012,48, 1580-1582
Article type
Communication

Iron-catalysed, hydride-mediated reductive cross-coupling of vinyl halides and Grignard reagents

B. A. F. Le Bailly, M. D. Greenhalgh and S. P. Thomas, Chem. Commun., 2012, 48, 1580 DOI: 10.1039/C1CC14622J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.


Social activity

Search articles by author

Spotlight

Advertisements