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Issue 10, 2012
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FRET detection of amyloid β-peptide oligomerization using a fluorescent protein probe presenting a pseudo-amyloid structure

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Abstract

A FRET-based sensor protein presenting amyloid-like structures was successfully constructed for detecting the oligomeric assemblies of amyloid β-peptide (Aβ) wild-type and FAD-related mutants.

Graphical abstract: FRET detection of amyloid β-peptide oligomerization using a fluorescent protein probe presenting a pseudo-amyloid structure

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Publication details

The article was received on 26 Jul 2011, accepted on 24 Aug 2011 and first published on 12 Sep 2011


Article type: Communication
DOI: 10.1039/C1CC14552E
Citation: Chem. Commun., 2012,48, 1568-1570

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    FRET detection of amyloid β-peptide oligomerization using a fluorescent protein probe presenting a pseudo-amyloid structure

    T. Takahashi and H. Mihara, Chem. Commun., 2012, 48, 1568
    DOI: 10.1039/C1CC14552E

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