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Issue 3, 2012

Highly enantioselective Friedel–Crafts alkylation reaction catalyzed by rosin-derived tertiary amine–thiourea: synthesis of modified chromanes with anticancer potency

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Abstract

We present herein for the first time the synthesis and preliminary biological evaluation of various modified chromanesvia a rosin-derived tertiary amine–thiourea-catalyzed highly enantioselective Friedel–Crafts alkylation reaction.

Graphical abstract: Highly enantioselective Friedel–Crafts alkylation reaction catalyzed by rosin-derived tertiary amine–thiourea: synthesis of modified chromanes with anticancer potency

Supplementary files

Article information


Submitted
20 Jul 2011
Accepted
01 Nov 2011
First published
14 Nov 2011

Chem. Commun., 2012,48, 446-448
Article type
Communication

Highly enantioselective Friedel–Crafts alkylation reaction catalyzed by rosin-derived tertiary aminethiourea: synthesis of modified chromanes with anticancer potency

X. Jiang, L. Wu, Y. Xing, L. Wang, S. Wang, Z. Chen and R. Wang, Chem. Commun., 2012, 48, 446 DOI: 10.1039/C1CC14379D

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