Issue 12, 2012
From the journal:

Analyst

Ultrasensitive detection of potassium ions based on target induced DNA conformational switch enhanced fluorescence polarization

Kun Hu,*a   Yong Huang,a   Shulin Zhao,*a   Jianniao Tian,a   Qiang Wu,a   Guohai Zhanga  and  Jing Jianga  

* Corresponding authors

a Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education), College of Chemistry and Chemical Engineering, Guangxi Normal University, Guilin, China
E-mail: hukun216@163.com, zhaoshulin001@163.com
Fax: +86-773-2120958
Tel: +86-773-2120958

Abstract

We have developed a simple, highly sensitive and selective fluorescence polarization assay for the detection of potassium ions based on target induced DNA conformational switch from hairpin to G-quadruplex enhanced fluorescence polarization. The assay was applied in the detection of low nM concentrations of potassium ions and was highly selective over other cations.

Graphical abstract: Ultrasensitive detection of potassium ions based on target induced DNA conformational switch enhanced fluorescence polarization

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/C2AN35416K
Article type
Communication
Submitted
19 Feb 2012
Accepted
23 Apr 2012
First published
24 Apr 2012

Analyst, 2012,137, 2770-2773

Permissions

Request permissions

Ultrasensitive detection of potassium ions based on target induced DNA conformational switch enhanced fluorescence polarization

K. Hu, Y. Huang, S. Zhao, J. Tian, Q. Wu, G. Zhang and J. Jiang, Analyst, 2012, 137, 2770 DOI: 10.1039/C2AN35416K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements