On-chip electromembrane extraction for monitoring drug metabolism in real time by electrospray ionization mass spectrometry
Abstract
A temperature controlled (37 °C) metabolic reaction chamber with a volume of 1 mL was coupled directly to
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* Corresponding authors
a
School of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2100 Copenhagen, Denmark
E-mail:
njp@farma.ku.dk
Tel: +45 35336184
b ADME Department, Diabetes Biology and Pharmacology, Novo Nordisk A/S, Maaloev, Denmark
c School of Pharmacy, The Faculty of Mathematics and Natural Sciences, University of Oslo, P.O. Box 1068 Blindern, 0316 Oslo, Norway
A temperature controlled (37 °C) metabolic reaction chamber with a volume of 1 mL was coupled directly to
N. J. Petersen, J. S. Pedersen, N. N. Poulsen, H. Jensen, C. Skonberg, S. H. Hansen and S. Pedersen-Bjergaard, Analyst, 2012, 137, 3321 DOI: 10.1039/C2AN35264H
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