Jump to main content
Jump to site search

Issue 45, 2012
Previous Article Next Article

Nematic growth of microtubules that changed into giant spiral structure through partial depolymerization and subsequent dynamic ordering

Author affiliations

Abstract

In a long capillary cell with temperature gradient, tubulin dimers with alpha and beta subunits polymerized according to the preferential polarity, i.e., the anisotropic spiral addition of the dimers to the beta-terminated “plus end” dominated the formation of microtubules. As the result, the helical hollow cylinders generated the oriented nematic liquid crystalline structure with centimeter-length. In the next stage, where microtubules were under the partial polymerization/depolymerization equilibrium due to the concentration fluctuation, the dynamic rearrangement of microtubules such as their shortening (depolymerization) and subsequent tilting of orientation axis caused the structural change from the oriented nematic liquid crystalline structure to some giant spiral structure which was subjected by the ordered dipole and the helical chirality of microtubules.

Graphical abstract: Nematic growth of microtubules that changed into giant spiral structure through partial depolymerization and subsequent dynamic ordering

Back to tab navigation

Supplementary files

Publication details

The article was received on 20 Jul 2012, accepted on 06 Sep 2012 and first published on 26 Sep 2012


Article type: Paper
DOI: 10.1039/C2SM26675J
Soft Matter, 2012,8, 11544-11551

  •   Request permissions

    Nematic growth of microtubules that changed into giant spiral structure through partial depolymerization and subsequent dynamic ordering

    K. Shigehara, H. Kudoh, S. Mori, Y. Tamura, A. Kakugo, R. Kawamura, H. Furukawa, J. P. Gong, H. Masunaga, T. Masui, S. Koizumi and K. Shikinaka, Soft Matter, 2012, 8, 11544
    DOI: 10.1039/C2SM26675J

Search articles by author

Spotlight

Advertisements