Issue 25, 2012

Synthesis of 2,3-dihydro-4-pyranones from epoxidesvia intermolecular [4+2] cycloaddition reaction

Abstract

An efficient synthesis of 2,3-dihydro-4-pyranones from epoxides and 3-alkoxycyclobutanones via an intermolecular [4+2] cycloaddition reaction, mediated by boron trifluoride etherate has been developed. The reaction is diastereoselective and gives trans diastereomers in excess.

Graphical abstract: Synthesis of 2,3-dihydro-4-pyranones from epoxides via intermolecular [4+2] cycloaddition reaction

Supplementary files

Article information

Article type
Paper
Submitted
04 Jun 2012
Accepted
10 Aug 2012
First published
13 Aug 2012

RSC Adv., 2012,2, 9398-9402

Synthesis of 2,3-dihydro-4-pyranones from epoxides via intermolecular [4+2] cycloaddition reaction

K. Indukuri, S. Bondalapati, S. Sultana and A. K. Saikia, RSC Adv., 2012, 2, 9398 DOI: 10.1039/C2RA21468G

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