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Issue 9, 2012
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Unexpected enzyme-catalyzed regioselective acylation of flavonoid aglycones and rapid product screening

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Abstract

Unprecedented regioselective acylation of flavonoid aglycones was achieved using Candida antarcticalipase B (CALB). The rapid screening of product formation was performed by the use of the high resolution phenol-type OH 1H NMR spectral region recorded after the addition of picric acid.

Graphical abstract: Unexpected enzyme-catalyzed regioselective acylation of flavonoid aglycones and rapid product screening

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Publication details

The article was received on 23 Oct 2011, accepted on 14 Dec 2011 and first published on 19 Dec 2011


Article type: Communication
DOI: 10.1039/C2OB06784F
Org. Biomol. Chem., 2012,10, 1739-1742

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    Unexpected enzyme-catalyzed regioselective acylation of flavonoid aglycones and rapid product screening

    E. Kyriakou, A. Primikyri, P. Charisiadis, M. Katsoura, I. P. Gerothanassis, H. Stamatis and A. G. Tzakos, Org. Biomol. Chem., 2012, 10, 1739
    DOI: 10.1039/C2OB06784F

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