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Issue 34, 2012
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A NIR BODIPY dye bearing 3,4,4a-trihydroxanthene moieties

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Abstract

A novel 3,4,4a-trihydroxanthene-fused pyrrole 2 was synthesized by the reaction of 2,3,4,4a-tetrahydro-1H-xanthen-1-one with 3-phenyl-2H-azirine in the presence of LDA. Utilizing this pyrrole 2, a NIR BODIPY 1 (λabs = 732 nm, λem = 747 nm) has been prepared. The new BODIPY 1 was stable, non-cytotoxic, and suited to labeling living cells for imaging assay in the NIR region.

Graphical abstract: A NIR BODIPY dye bearing 3,4,4a-trihydroxanthene moieties

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Publication details

The article was received on 14 May 2012, accepted on 06 Jul 2012 and first published on 06 Jul 2012


Article type: Paper
DOI: 10.1039/C2OB26218E
Org. Biomol. Chem., 2012,10, 6861-6865

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    A NIR BODIPY dye bearing 3,4,4a-trihydroxanthene moieties

    X. Jiang, R. Gao, Y. Yue, G. Sun and W. Zhao, Org. Biomol. Chem., 2012, 10, 6861
    DOI: 10.1039/C2OB26218E

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