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Issue 15, 2012
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Bioinspired organocatalytic asymmetric reactions

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Abstract

Several small organic molecule catalysts are reminiscent of natural enzymes in their mode of action and substrate interaction/activation. This striking similarity has been a great source of inspiration for the development of new organocatalytic asymmetric processes. A few representative examples, mostly dealing with catalysts interacting through multiple hydrogen-bonds (synthetic oxyanion holes), are highlighted in this perspective.

Graphical abstract: Bioinspired organocatalytic asymmetric reactions

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Article information


Submitted
05 Dec 2011
Accepted
27 Jan 2012
First published
27 Jan 2012

Org. Biomol. Chem., 2012,10, 2911-2922
Article type
Perspective

Bioinspired organocatalytic asymmetric reactions

L. Bernardi, M. Fochi, M. Comes Franchini and A. Ricci, Org. Biomol. Chem., 2012, 10, 2911
DOI: 10.1039/C2OB07037E

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