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Issue 8, 2012
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Natural products from Cephalotaxus sp.: chemical diversity and synthetic aspects

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Abstract

Covering: up to 2012

The Cephalotaxus genus belongs to the Cephalotaxaceae family of conifers. Over the past decades it has proved to be a fruitful source of interesting natural products, especially alkaloids (cephalotaxine esters) and terpenoids (abietanes, troponoids), which often display medicinal properties, especially in the anticancer area. Homoharringtonine is active against some orphan leukaemia and is nowadays approaching marketability. A phytochemical update will be provided and the total synthesis of alkaloids and terpenoids will be discussed in detail.

Graphical abstract: Natural products from Cephalotaxus sp.: chemical diversity and synthetic aspects

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Publication details

The article was received on 15 Mar 2012 and first published on 20 Jun 2012


Article type: Review Article
DOI: 10.1039/C2NP20037F
Nat. Prod. Rep., 2012,29, 845-869

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    Natural products from Cephalotaxus sp.: chemical diversity and synthetic aspects

    H. Abdelkafi and B. Nay, Nat. Prod. Rep., 2012, 29, 845
    DOI: 10.1039/C2NP20037F

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