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Issue 7, 2012
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Cellular transport and homeostasis of essential and nonessential metals

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Abstract

Metals can have a number of detrimental or beneficial effects in the cell, but first they must get in. Organisms have evolved transport mechanisms to get metals that are required, or essential into the cell. Nonessential metals often enter the cell through use of the machinery provided for essential metals. Much work has been done to advance our understanding of how these metals are transported across plasma and organelle membranes. This review provides an overview of essential and nonessential metal transport and homeostatic processes.

Graphical abstract: Cellular transport and homeostasis of essential and nonessential metals

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Publication details

The article was received on 19 Dec 2011, accepted on 03 Feb 2012 and first published on 06 Feb 2012


Article type: Minireview
DOI: 10.1039/C2MT00185C
Metallomics, 2012,4, 593-605

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    Cellular transport and homeostasis of essential and nonessential metals

    E. J. Martinez-Finley, S. Chakraborty, S. J. B. Fretham and M. Aschner, Metallomics, 2012, 4, 593
    DOI: 10.1039/C2MT00185C

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