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Issue 10, 2012
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An anion structure–activity relationship of imidazolium-based synthetic transporters

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Abstract

We have developed imidazolium-based salts as a new recognition motif with strong anionophoric properties across phospholipid bilayers. We present here factors intrinsic to the imidazolium salts that allow the modulation of their ionophoric properties. We also report the kinetic and thermodynamic parameters of the most active imidazolium salt.

Graphical abstract: An anion structure–activity relationship of imidazolium-based synthetic transporters

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Publication details

The article was received on 27 Apr 2012, accepted on 17 Jun 2012 and first published on 18 Jun 2012


Article type: Concise Article
DOI: 10.1039/C2MD20107K
Med. Chem. Commun., 2012,3, 1231-1234

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    An anion structure–activity relationship of imidazolium-based synthetic transporters

    C. Elie, M. Charbonneau and A. R. Schmitzer, Med. Chem. Commun., 2012, 3, 1231
    DOI: 10.1039/C2MD20107K

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