Issue 10, 2012

An anion structure–activity relationship of imidazolium-based synthetic transporters

Abstract

We have developed imidazolium-based salts as a new recognition motif with strong anionophoric properties across phospholipid bilayers. We present here factors intrinsic to the imidazolium salts that allow the modulation of their ionophoric properties. We also report the kinetic and thermodynamic parameters of the most active imidazolium salt.

Graphical abstract: An anion structure–activity relationship of imidazolium-based synthetic transporters

Supplementary files

Article information

Article type
Concise Article
Submitted
27 Apr 2012
Accepted
17 Jun 2012
First published
18 Jun 2012

Med. Chem. Commun., 2012,3, 1231-1234

An anion structure–activity relationship of imidazolium-based synthetic transporters

C. Elie, M. Charbonneau and A. R. Schmitzer, Med. Chem. Commun., 2012, 3, 1231 DOI: 10.1039/C2MD20107K

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