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Issue 1, 2012
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Inhibitors of Stat5 protein signalling

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Abstract

Evidence shows that signal transducer and activator of transcription 5 (Stat5) protein, a member of the STAT family of signalling proteins, plays a pivotal role in the progression of many human cancers including acute myeloid leukemias and prostate cancer. This mini-review outlines progress made towards identifying agents capable of silencing aberrant Stat5 signalling.

Graphical abstract: Inhibitors of Stat5 protein signalling

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Article information


Submitted
07 Jul 2011
Accepted
25 Aug 2011
First published
03 Oct 2011

Med. Chem. Commun., 2012,3, 22-27
Article type
Review Article

Inhibitors of Stat5 protein signalling

A. A. Cumaraswamy, A. Todic, D. Resetca, M. D. Minden and P. T. Gunning, Med. Chem. Commun., 2012, 3, 22
DOI: 10.1039/C1MD00175B

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