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Issue 24, 2012
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DropletMicroarray: facile formation of arrays of microdroplets and hydrogel micropads for cell screening applications

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Abstract

We describe a one-step method for creating thousands of isolated pico- to microliter-sized droplets with defined geometry and volume. Arrays of droplets are instantly formed as liquid moves along a superhydrophilic–superhydrophobic patterned surface. Bioactive molecules, nonadherent cells, or microorganisms can be trapped in the fully isolated microdroplets for high-throughput screening, or in hydrogel micropads for screening in 3D microenvironments.

Graphical abstract: DropletMicroarray: facile formation of arrays of microdroplets and hydrogel micropads for cell screening applications

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Publication details

The article was received on 14 Aug 2012, accepted on 11 Oct 2012 and first published on 12 Oct 2012


Article type: Paper
DOI: 10.1039/C2LC40921F
Lab Chip, 2012,12, 5218-5224

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    DropletMicroarray: facile formation of arrays of microdroplets and hydrogel micropads for cell screening applications

    E. Ueda, F. L. Geyer, V. Nedashkivska and P. A. Levkin, Lab Chip, 2012, 12, 5218
    DOI: 10.1039/C2LC40921F

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