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Issue 9, 2012
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New “one-step” method for the simultaneous synthesis and anchoring of organic monolith inside COC microchip channels

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Abstract

A new method for monolith synthesis and anchoring inside cyclic olefin copolymer (COC) microchannels in a single step is proposed. It is shown that type I photoinitiators, typically used in a polymerization mixture to generate free radicals during monolith synthesis, can simultaneously act as type II photoinitiators and react with the plastic surface through hydrogen abstraction. This mechanism is used to “photograft” poly(ethylene glycol) methacrylate (PEGMA) on COC surfaces. Contact angle measurements were used to observe the changes in surface hydrophilicity when increasing initiator concentration and irradiation duration. The ability of type I photoinitiators to synthesize and anchor a monolith inside COC microchannels in a single step was proved through SEM observations. Different concentrations of photoinitiators were tried. Finally, electrochromatographic separations of polycyclic aromatic hydrocarbons were realized to illustrate the beneficial effect of anchoring on chromatographic performances. The versatility of the method was demonstrated with two widely used photoinitiators: benzoin methyl ether (BME) and azobisisobutyronitrile (AIBN).

Graphical abstract: New “one-step” method for the simultaneous synthesis and anchoring of organic monolith inside COC microchip channels

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Article information


Submitted
06 Dec 2011
Accepted
09 Feb 2012
First published
13 Feb 2012

Lab Chip, 2012,12, 1680-1685
Article type
Paper

New “one-step” method for the simultaneous synthesis and anchoring of organic monolith inside COC microchip channels

Y. Ladner, A. Bruchet, G. Crétier, V. Dugas, J. Randon and K. Faure, Lab Chip, 2012, 12, 1680
DOI: 10.1039/C2LC21211K

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