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Issue 4, 2012
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Polymer encapsulated conjugated polymernanoparticles for fluorescence bioimaging

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Abstract

The recent advances of in vitro and in vivo bioimaging require novel classes of fluorescent probes with high fluorescence, good photostability and low cytotoxicity. Conjugated polymer based fluorescent nanoparticles as an alternative to conventional fluorescent probes have attracted wide attention in bioimaging due to their intrinsic merits. This feature article reviews the recent development of polymer encapsulated conjugated polymer nanoparticles in bioimaging applications. Through emulsion or nanoprecipitation, polymeric nanoparticles with desired optical properties and surface functional groups are obtained to meet specific requirements of various imaging tasks. Fine-tuning of the conjugated polymer structure and polymeric encapsulation matrix will lead to advanced fluorescent probes for in vitro and in vivo bioimaging applications.

Graphical abstract: Polymer encapsulated conjugated polymer nanoparticles for fluorescence bioimaging

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Article information


Submitted
06 Sep 2011
Accepted
12 Oct 2011
First published
24 Nov 2011

J. Mater. Chem., 2012,22, 1257-1264
Article type
Feature Article

Polymer encapsulated conjugated polymer nanoparticles for fluorescence bioimaging

K. Li and B. Liu, J. Mater. Chem., 2012, 22, 1257 DOI: 10.1039/C1JM14397B

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