Jump to main content
Jump to site search

Issue 11, 2012
Previous Article Next Article

Transition metal-free, NaOtBu-O2-mediated one-pot cascade oxidation of allylic alcohols to α,β-unsaturated carboxylic acids

Author affiliations

Abstract

We developed a protocol for the transition metal-free, direct oxidation of allylic alcohols using the simple base NaOtBu under an oxygen atmosphere. The NaOtBu–O2 system exhibited unprecedented activity and selectivity in this oxidation reaction. In particular, a competing epoxidation reaction was suppressed under these conditions.

Graphical abstract: Transition metal-free, NaOtBu-O2-mediated one-pot cascade oxidation of allylic alcohols to α,β-unsaturated carboxylic acids

Back to tab navigation

Supplementary files

Publication details

The article was received on 16 May 2012, accepted on 03 Sep 2012 and first published on 04 Sep 2012


Article type: Communication
DOI: 10.1039/C2GC36203A
Green Chem., 2012,14, 2996-2998

  •   Request permissions

    Transition metal-free, NaOtBu-O2-mediated one-pot cascade oxidation of allylic alcohols to α,β-unsaturated carboxylic acids

    S. M. Kim, Y. S. Kim, D. W. Kim and J. W. Yang, Green Chem., 2012, 14, 2996
    DOI: 10.1039/C2GC36203A

Search articles by author

Spotlight

Advertisements