Issue 6, 2012

Solvent- and catalyst-free synthesis of new hydroxylated trisubstituted pyridines under microwave irradiation

Abstract

A facile solvent- and catalyst-free method for the synthesis of a series of new hydroxylated 2,4,6-trisubstituted pyridines under microwave irradiation was developed. The expected products were obtained through a simplified purification process without protection of the hydroxyl group. UV-Vis and fluorescence spectra of these conjugated multi-hydroxyl compounds were also investigated.

Graphical abstract: Solvent- and catalyst-free synthesis of new hydroxylated trisubstituted pyridines under microwave irradiation

Supplementary files

Article information

Article type
Paper
Submitted
18 Feb 2012
Accepted
10 Apr 2012
First published
13 Apr 2012

Green Chem., 2012,14, 1796-1798

Solvent- and catalyst-free synthesis of new hydroxylated trisubstituted pyridines under microwave irradiation

G. Yin, Q. Liu, J. Ma and N. She, Green Chem., 2012, 14, 1796 DOI: 10.1039/C2GC35243E

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