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Issue 9, 2012
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Copper-catalyzed reductive amination of aromatic and aliphatic ketones with anilines using environmental-friendly molecular hydrogen

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Abstract

A convenient and practical copper-catalyzed reductive amination was discovered. In the presence of easily available and inexpensive Cu(OAc)2 various ketones react with anilines and molecular hydrogen to give the desired amines in high yields.

Graphical abstract: Copper-catalyzed reductive amination of aromatic and aliphatic ketones with anilines using environmental-friendly molecular hydrogen

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Article information


Submitted
15 Apr 2012
Accepted
13 Jun 2012
First published
14 Jun 2012

Green Chem., 2012,14, 2371-2374
Article type
Communication

Copper-catalyzed reductive amination of aromatic and aliphatic ketones with anilines using environmental-friendly molecular hydrogen

S. Werkmeister, K. Junge and M. Beller, Green Chem., 2012, 14, 2371
DOI: 10.1039/C2GC35565E

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